Halima Mouhib

Halima Mouhib

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Olfactory Research, Biomolecules, Conformational Sampling, Molecular Dynamics, Multi-scale Simulations

Dr. Halima Mouhib is associate professor in bioinformatics at the VU Amsterdam and co-leads the group together with Dr. Anton K. Feenstra. During her PhD, she specialized in the characterization of bioactive compounds at the RWTH Aachen University in Germany, and subsequently expanded her research focus towards structural bioinformatics. She obtained her habilitation at the University Paris-Est, and was awarded the Descartes-Huygens award 2020 by the Koninklijke Nederlandse Akademie van Wetenschappen, to study how odorants are absorbed from the gas-phase through binding proteins to mimic the absorption of fragrances in the nose. Since 2021, she is a junior member of the Institut Universitaire Francais. She is the main organizer of the AI4Biomed series on the VU Campus, and actively involved in the Amsterdam Institute of Molecular and Life Sciences. Starting February 2025, she joined the management team of the Computer Science Department as research portfolio holder.

[5] Massimiliano Paesani, Arthur G. Goetzee, Sanne Abeln, Halima Mouhib, Odorant Binding Proteins Facilitate the Gas-Phase Uptake of Odorants Through the Nasal Mucus, https://doi.org/10.1002/chem.202403058

[4] R. Dahmani, H. Sun, H. Mouhib, Quantifying soft degrees of freedom in volatile organic
compounds: insight from quantum chemistry and focused single molecule experiments, Phys.Chem. Chem. Phys. 2020, 22, 27850-27860.

[3] M. Baclayon, P. van Ulsen, H. Mouhib, M. Hashemi Shabestar, T. Verzijden, S. Abeln, W. H.
Roos, G. J. L. Wuite, Mechanical Unfolding of an Autotransporter Passenger Protein Reveals the Secretion Starting Point and Processive Transport Intermediates, ACS Nano 2016, 10(6), 5710–5719.

[2] G. Rossetti, F. Musiani, E. Abad, D. Dibenedetto, H. Mouhib, C.O. Fernandez, P. Carloni,
Conformational Ensemble of Human alpha-Synuclein Physiological Form Predicted by
Molecular Simulations, Phys. Chem. Chem. Phys. 2016, 18, 5702-5706.

[1] H. Mouhib, W. Stahl, M. Lüthy, M. Büchel, P. Kraft, Cassis Odor through Microwave Eyes:
Olfactory Properties and Gasphase Structures of all the Cassyrane Stereoisomers and its Dihydro Derivatives, Angew. Chem. Int. Ed. 2011, 50, 5576-5580.

NWO Open Competition Domain Science M23-1 (Main PI)
- ODORWISE: Unravelling Odorant Detection Mechanisms for Biosensors in Sustainable Healthcare, 2024-2028

Membre Junior 2021 de l'Institut universitaire de France (IUF)
- Research and Teaching grant. Issued by Institut Universitaire Francais (IUF) · Oct 2021

Descartes-Huygens Award 2020
- Prize to support the scientific/scholarly career of an excellent researcher in Franco-Dutch research. Issued by The Royal Netherlands Academy of Arts and Sciences (KNAW) and the Académie des Sciences · Feb 2021Issued by The Royal Netherlands Academy of Arts and Sciences (KNAW) and the Académie des Sciences · Feb 2021

Academic Staff