Evert Bosdriesz
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I’m an Assistant professor in Bioinformatics in the Computer Science department at the Vrije Universiteit Amsterdam.
I obtained my MSc in theoretical physics at the UvA, but evolved into a computational biologist. I did my PhD in the Systems Biology group of Bas Teusink and Frank Bruggeman, after which I did a postdoc in the Computational Cancer Biology group of Lodewyk Wessels at the Netherlands Cancer Institute.
My research focusses on computational approaches to understand signal transduction networks and the role they play in cancer. I'm particularly excited about the possibilities of novel single cell technologies. By using a combination of statistical and mechanistic modeling approaches, I aim to bridge the gap between “top down” bioinformatics and “bottom up” systems biology.
* Bioinformatics for Translational Medicine (This is a compulsory course in the Bioinformatics track of the Bioinformatics and Systems Biology Master from the VU and UvA.)
* Introduction to Bioinformatics (This is a compulsory course for 2th year BSc students Medische Natuurwetenschappen.)
* Member of the BioSB Education Committee
Bosdriesz, E., Fernandes Neto, J. M., Sieber, A., Bernards, R., Blüthgen, N. & Wessels, L. F. A. Identifying mutant-specific drug combinations using Comparative Network Reconstruction. bioRxiv 2020.12.17.423240 (2020). doi:10.1101/2020.12.17.423240
Fernandes Neto, J. M., Nadal, E., Bosdriesz, E., Ooft, S. N., Farre, L., McLean, C., Klarenbeek, S., Jurgens, A., Hagen, H., Wang, L., Felip, E., Martinez-Marti, A., Vidal, A., Voest, E., Wessels, L. F. A., van Tellingen, O., Villanueva, A. & Bernards, R. Multiple low dose therapy as an effective strategy to treat EGFR inhibitor-resistant NSCLC tumours. Nat. Commun. 11, 3157 (2020).
Bosdriesz, E., Prahallad, A., Klinger, B., Sieber, A., Bosma, A., Bernards, R., Blüthgen, N. & Wessels, L. F. A. Comparative Network Reconstruction using mixed integer programming. Bioinformatics 34, i997–i1004 (2018).
* SB@NL symposium poster prize (2th place) 2013
* FEBS Youth Travel Fund 2011
* Shell Theoretical Physics Stipend 2010