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Tag: Neurodegenerative diseases

Discovery of novel CSF biomarkers to predict progression in dementia using machine learning

Discovery of novel CSF biomarkers to predict progression in dementia using machine learning

We are excited to share our latest publication by Dea Gogishvili. The paper is a part of a special collection – artificial intelligence for personalised medicine. Here we explore the rate of cognitive decline in dementia patients to identify CSF biomarkers. Thanks to the co-authors for their valuable insights and dedication in bringing this project to life.

How sticky are our proteins? Quantifying hydrophobicity of the human proteome

How sticky are our proteins? Quantifying hydrophobicity of the human proteome

We are happy to share our recent publication by Juami Hermine Mariama van Gils,  Dea Gogishvili,  Jan van Eck,  Robbin Bouwmeester, Erik van Dijk, and Sanne Abeln. Check out the ISMB-ECCB talk by Juami van Gils and Dea Gogishvili on our YouTube channel. Abstract: Proteins tend to bury hydrophobic residues inside their core during the folding process to provide stability to the protein structure and to prevent aggregation. Nevertheless, proteins do expose some ‘sticky’ hydrophobic residues to the solvent. These residues can play an important functional…

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